The Nature's Souvenir for High-Altitude, all organic herbal plants with medicinal values.
Herbs found at high altitudes often possess unique biochemical composition because of their adaptation under extremely harsh environmental conditions, such as cold and low oxygen. These herbs are found to eradicate ailments from the root of the disease, in spite of age group, and are effective drugs with no side effects. Among the high-altitude herbs, Curcuma Longa, Cordyceps sinensis, Ganoderma lucidum, Hippophae spp., Rhodiola rosea, and Valeriana wallichii are the best known. These are reported to contain unique bioactive constituents such as cordycepin, ganoderic acid, omega fatty acids, rhodioflavonoside, valerinic acid, respectively. The application of an herb as an effective drug necessitates characterization of its formulations using various analytical techniques. This chapter highlights characterization of prepared extracts, fractions, and/or isolated bioactive compounds from herbal sources using chromatographic and spectroscopic analytical techniques.
A Review of Its Chemical Composition, Quality Control, Bioactivity, and Pharmaceutical Application
Curcuma Longa, the only 1 kinds in 12 different kinds of Curcuma genus has been most researched and clinical trial (the rhizome of Curcuma longa Linn.), it has been used as in medicinal preparations for various diseases including cough, diabetic wounds, hepatic and cardiovascular disorders in Eastern civilization for a long time. Curcuminoids is the major components of curcuma, which have shown various bioactivities and promising results in various research investigations. Particularly, curcumin has demonstrated powerful efficacy as an anticancer agent, which possesses antiinflammatory, antioxidant, anti-Alzheimer, and anticancer activities in both preclinical and clinical studies.
Moreover, curcumin has hepatoprotective, neuroprotective, cardioprotective, hypoglycemic, antirheumatic, and antidiabetic activities. Recently research indicated that the ar-turmerone, α-turmerone, and β-turmerone were the biologically active constituents in the essential oil, and proved their antimicrobial, antioxidative, antiinflammatory activity, and anticancer potentials. Turmeric oil is also widely used in pharmaceutical and cosmetic applications. Therefore, both curcuminoids and volatile components are the basis for healthy efficiencies of Curcuma Longa.
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