Beneficial effects of BBE Green Tea Extract P5000
一般來說，草藥是不同化合物的複雜混合物，它們通常以協同方式發揮其全部有益作用，然而，與西方藥物相比，相對較少的草藥已經得到很好的表徵，並且在系統的臨床試驗中證明了它們的功效。這篇綜述文章重點介紹了最近關於綠茶及其兒茶素在體外、體內和離體系統中的功效、作用機制和副作用的研究。
https://pubmed.ncbi.nlm.nih.gov/18567057/
綠茶素對肝臟和腎臟中衰老介導的氧化還原失衡具有極強的保護作用。
本研究探討綠茶提取物的兒茶素成分及其對衰老小鼠肝臟和腎臟中衰老介導的氧化還原失衡的保護作用。結果表明，本研究分析的綠茶提取物中的7種兒茶素可在30 min內完全分離，綠茶提取物中兒茶素的主要成分為EGCG、EGC和ECG。在綠茶提取物的抗衰老作用方面，以 125、625 和 1250 mg/kg 的劑量補充綠茶提取物 4 周顯著緩解了衰老介導的氧化還原失衡，從顯著 ( p< 0.05) 降低血清中硫代巴比妥酸反應物質 (TBARS) 和蛋白質羰基化合物的水平，並增加血漿中的穀胱甘肽 (GSH) 和總硫醇含量。此外，肝腎蛋白羰基水平顯著降低（p < 0.05），超氧化物歧化酶（SOD）、過氧化氫酶、葡萄糖-6-磷酸脫氫酶（G6PD）、穀胱甘肽過氧化物酶（GSH-Px）和穀胱甘肽還原酶（GSH -Rd) 在肝臟和腎臟中顯著升高 ( p< 0.05)。總體而言，這些結果清楚地表明，綠茶提取物通過抑制脂質和蛋白質的氧化損傷並增加器官中抗氧化酶的活性，對小鼠肝臟和腎臟中衰老介導的氧化還原失衡具有極強的保護作用。
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751114/
This study investigates the catechin composition and protective effect of green tea extract on senescence-mediated redox imbalance in the livers and kidneys of aged mice. The results showed that the seven catechins in the green tea extract analyzed in this study could be completely separated within 30 min and the main components of catechins in green tea extract were EGCG, EGC and ECG. In terms of the anti-senescence effects of green tea extract, green tea extract supplementation at doses of 125, 625 and 1250 mg/kg for 4 weeks significantly alleviated the senescence-mediated redox imbalance, as exhibited from significantly (p < 0.05) reduced thiobarbituric acid-reactive substances (TBARS) and protein carbonyls levels in the serum, and increased glutathione (GSH) and total thiols contents in the plasma. Additionally, hepatic and renal protein carbonyls levels were significantly diminished (p < 0.05) and the activities of superoxide dismutase (SOD), catalase, glucose-6-phosphate dehydrogenase (G6PD), glutathione peroxidase (GSH-Px) and glutathione reductase (GSH-Rd) in the liver and kidney were remarkably elevated (p < 0.05). Overall, these results clearly show that green tea extract exhibits extremely potent protective effects against senescence-mediated redox imbalance in the livers and kidneys of mice by inhibiting oxidative damage of lipids and proteins and increasing the activities of antioxidant enzymes in organs.
2) 抗氧化 Antioxidative
https://pubmed.ncbi.nlm.nih.gov/11239828/
https://www.sciencedirect.com/science/article/abs/pii/S1532045600001927?via%3Dihub